Garvan Institute of Medical Research brings together world leading scientists and clinicians, collaborating locally and globally, to advance our understanding of disease, particularly cancer, autoimmunity and genetic disorders. Garvan is a global leader in fundamental biomedical research and its translation. Our mission is to make discoveries that will improve health for all. Building on our scientific strengths in genomics, cancer and immunology, enabled by cutting-edge technology and world-class facilities, and the support of our passionate Garvan family, our researchers and professional staff, we will drive more of our discoveries to clinical and societal impact. At Garvan, we see a future where all diseases can be prevented, treated or cured. Everyone is touched by disease. Our discoveries today will lead to better health tomorrow. THE OPPORTUNITY We are seeking an experienced and motivated Research Officer to contribute to the development of next generation protein therapeutics, including multispecifics, antibody–drug conjugates, immunotoxins, and peptides. This role is critical for delivering high quality recombinant proteins to support in vitro and in vivo characterisation of therapeutic candidates and target molecules. You will contribute to end to end biologics development, from early concept through to translational studies, within a newly established biologics platform integrated into a leading healthcare and research ecosystem. The successful candidate will collaborate with platform members, crossfunctional teams, and external partners while mentoring junior scientists. Salary: Up to $108,000 (depending on experience) 14% super salary packaging Employment Type: 2 year fixed-term contract with possibility to extend SNAPSHOT OF BENEFITS Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses $2,650 meals/accom) Ample opportunities for on-going training and development Stimulating, diverse and highly international research environment Flexible work arrangements e.g. start / finish times 18 weeks paid parental leave for both parents including paid superannuation A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave Discounted Health Insurance Lifestyle discounts with our community partners WHAT YOU WILL DO Under the guidance of senior staff, the successful candidate will: Protein Expression, Purification & Analytics Design and generate expression constructs for recombinant protein production. Develop, optimise, and execute protein purification strategies including affinity, ion exchange, HIC, SEC, and multistep workflows. Perform analytical characterisation (SEC-MALS, DLS, DSF, Mass photometry, HPLC/UHPLC, SDS-PAGE, CE-SDS, binding assays). Evaluate and troubleshoot protein quality attributes. Support analytical method development and workflow optimisation. Maintain accurate documentation and data integrity in ELNs. Experimental Planning & Execution Design hypothesis driven experiments for biologics development. Independently execute complex wet lab workflows. Analyse, interpret, and present scientific data. Identify risks, troubleshoot challenges, and propose solutions. Team Leadership, Training & Stakeholder Engagement Train and mentor junior staff. Collaborate with cross-functional teams and CROs. Communicate scientific outcomes to technical and non-technical audiences. Participate in lab meetings and scientific forums. Innovation & Continuous Improvement Stay current with scientific literature and emerging technologies. Drive adoption of cutting edge purification/analytical technologies. Contribute to IP, publications, and internal scientific outputs. Support process optimisation and implementation of best practices. ABOUT YOU The key skills and experience include: Education: Ph.D. in Protein Engineering, Structural Biology, Biochemistry, Molecular Biology, or related field. Technical Expertise: Experience in protein engineering, expression, purification, and characterisation. Strong hands-on experience with FPLC and HPLC/UHPLC. Experience with biophysical and analytical techniques (DSF, DLS, SEC-MALS, analytical SEC, binding analysis). Experience training junior staff and contributing to collaborative teams. Familiarity with molecular biology and biochemistry assays. Attributes High integrity and accountability. Strong communication and documentation skills. Effective stakeholder engagement. Creative problem solving and adaptability. Commitment to health and safety. ABOUT GARVAN Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia’s largest and most highly regarded MRI’s. Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome. We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease. Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging. We are always looking for culture ‘add’, not culture ‘fit’ and are building diverse teams with great sets of complementary styles and skills to help deliver our important work effectively. HOW TO APPLY To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. We are reviewing applications as they are received. If you think you’re the right person for this role, we’d love to hear how your capabilities, achievements and experience set you apart. Only applicants with full working rights in Australia are eligible to apply for this role.
