Full time fixed term contract for one year with possible extension Be a part of a research team who are ambitious, enthusiastic, cooperative, and dedicated group working towards finding cures for disease Base Salary starting from $ 108,557 1 7% superannuation About the opportunity The Sydney Pharmacy School is a globally recognised leading centre for pharmacy research and education. Our teams of researchers lead key internationally competitive research from molecules to medicines, from patient to policy, across a range of therapeutic areas. The University is seeking to employ a Laboratory Manager (HEO 7) to join a lab led by Professor Adam Walker, which focuses on molecular, biochemical, cellular, and mouse model studies of the causes and potential treatments for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) and frontotemporal dementia. We are looking for a highly motivated and experienced Laboratory Manager to join our dynamic team. The successful candidate will be responsible for overseeing the daily operations of our state-of-the-art laboratory, ensuring that all research activities are conducted efficiently and safely. This role requires strong leadership skills, excellent organizational abilities, and a deep understanding of laboratory practices and protocols. The incumbent will be based in the newly renovated Charles Perkins Centre located on the Camperdown campus. They will work both independently and cooperatively, with access to a dedicated support network and superb neuroscience research facilities, to forge new research directions, make important discoveries, and publish high-profile findings. Support will be provided for career development and leadership opportunities Your key responsibilities will be to: Manage and supervise laboratory staff, including training, scheduling, and performance evaluations Ensure compliance with all safety regulations and laboratory protocols. Oversee the maintenance and calibration of laboratory equipment Coordinate and manage research projects, ensuring timely completion and accurate documentation Develop and implement standard operating procedures (SOPs) for laboratory activities Monitor inventory levels and order supplies as needed Collaborate with researchers and other departments to support ongoing projects and initiatives Maintain accurate records of laboratory activities and prepare reports as required Undertake laboratory research including biochemical, cell biology, microscopy, cell and iPSC neuron culture, tissue and animal analysis, and virus production focused on neurodegenerative disease mechanisms. About you Bachelor's degree in a relevant scientific discipline Minimum of 15 years of experience in a laboratory setting, with at least 2 years in a supervisory or managerial role Minimum of 5 years of experience in the study of cell, iPSC-derived neuron and mouse models of TDP-43 pathology related to motor neuron disease and frontotemporal dementia Experience in tissue culture, primary neuron culture, iPSC-derived neuron culture, lentivirus production, CRISPR/Cas9/Cas13d gene activation/knockout/knockdown, FACS and other flow techniques, CRISPR whole genome screening, high throughput live cell imaging, protein solubility assays, immunoprecipitation and pulldown, endogenous gene tagged cell lines, biotin-tagging mass spectrometry sample preparation, immunoblotting and immunocytochemistry, fluorescence and confocal microscopy, mouse genotyping database management, transgenic mouse models of TDP-43 pathology, AAV mouse models of TDP-43 pathology Success in securing external funding such as to attend MND research conference/s Success in generation of scientific results leading to external competitive research grants Experience in presentation of scientific results at MND research conference/s Track record of engagement with philanthropic agencies and fundraising activities Track record of multiple research publications on topics of TDP-43 pathology and MND Experience in management of laboratory equipment and training including infrared membrane scanners and high frequency rapid RNA/protein extraction equipment Strong knowledge of laboratory safety protocols and best practices Excellent organizational and time-management skills Ability to lead and motivate a team Strong communication and interpersonal skills Proficiency in using laboratory management software and tools. Sponsorship / work rights for Australia Work Rights: you must have unrestricted work rights in Australia for the duration of this employment to apply. Visa sponsorship is not available for this appointment. Pre-employment checks Your employment is conditional upon the completion of all role required pre-employment or background checks in terms satisfactory to the University. Similarly, your ongoing employment is conditional upon the satisfactory maintenance of all relevant clearances and background check requirements. If you do not meet these conditions, the University may take any necessary step, including the termination of your employment. EEO statement At the University of Sydney, our shared values are trust, accountability and excellence and we strive to be a place where everyone can thrive. We are committed to creating a University community that thrives through diversity and reflects the wider community that we serve. We deliver on this through our commitment to diversity and inclusion , evidenced by our people and culture programs, as well as key strategies to increase participation and support the careers of Aboriginal and Torres Strait Islander People , women , people living with a disability , people from culturally and linguistically diverse backgrounds , and those who identify as LGBTIQ . We welcome applications from candidates from all backgrounds. We are proud to be recognised as an Australian Workplace Equality Index (AWEI) Gold employer. Find out more about our work on diversity and inclusion . How to apply Applications (including a cover letter, CV, and any additional supporting documentation) can be submitted via the Apply button at the top of the page. For employees of the University or contingent workers, please login into your Workday account and navigate to the Career icon on your Dashboard. Click on USYD Find Jobs and apply. For a confidential discussion about the role, or if you require reasonable adjustment or any documents in alternate formats, please contact Rachel Yazigi Recruitment Operations by email to rachel.yazigi@sydney.edu.au. © The University of Sydney The University reserves the right not to proceed with any appointment. Click to view the Position Description for this role. Applications Close Monday 19 May 2025 11:59 PM
